Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTK2 All Species: 35.76
Human Site: Y180 Identified Species: 78.67
UniProt: Q05397 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05397 NP_005598.3 1052 119233 Y180 C L E I R R S Y W E M R G N A
Chimpanzee Pan troglodytes XP_001147699 1096 124125 Y224 C L E I R R S Y W E M R G N A
Rhesus Macaque Macaca mulatta XP_001093060 1097 123900 Y224 C L E I R R S Y W E M R G N A
Dog Lupus familis XP_856301 1068 120990 Y180 C L E I R R S Y W E M R G N A
Cat Felis silvestris
Mouse Mus musculus P34152 1090 123518 Y180 C L E I R R S Y W E M R G N A
Rat Rattus norvegicus O35346 1055 119698 Y180 C L E I R R S Y W E M R G N A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510393 1059 119735 Y180 C L E I R R S Y W E M R G N A
Chicken Gallus gallus Q00944 1053 119189 Y180 C L E I R R S Y G E M R G N A
Frog Xenopus laevis Q91738 1068 121137 Y180 C L E I R R S Y G E M R G N A
Zebra Danio Brachydanio rerio O13147 500 55892
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120873 1165 130750 F185 C L E I R Y F F K D M Q Q I A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.8 93.2 95.4 N.A. 93.7 96.6 N.A. 92.6 94.6 88.7 20.7 N.A. N.A. 37.5 N.A. N.A.
Protein Similarity: 100 95.8 93.8 97 N.A. 95.1 98.5 N.A. 95.3 97.6 93.9 31.6 N.A. N.A. 54.9 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 93.3 0 N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 93.3 0 N.A. N.A. 66.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 91 % A
% Cys: 91 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 91 0 0 0 0 0 0 82 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 19 0 0 0 82 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 91 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 0 91 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 91 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 82 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % Q
% Arg: 0 0 0 0 91 82 0 0 0 0 0 82 0 0 0 % R
% Ser: 0 0 0 0 0 0 82 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 64 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 82 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _